NexGen Blog

The NexGen Blog is filled with informational resources to support those who own or care for equines, wildlife, companion animals and zoo animals.
Companion Animals

The NexGen Blog is filled with informational resources to support those who own or care for equines, wildlife, companion animals and zoo animals.
Equine

This section of our blog focuses on equine health conditions and treatments. We answer questions from veterinarians and animal owners as well as providing information and education. We cover topics such as antibiotics, pain management, breeding, sedation, weight, and more. Be sure to sign up to be notified when new posts are added to a topic that is important to you.
Non-Domestics & Exotics

This section of our blog is dedicated to providing information and education for zoo and wildlife handlers on health conditions, treatments, and compounds for non-domestic and exotic animals, including topics about antibiotics, reversals, immobilization & sedation and steroids. Be sure to sign up to be notified when new posts are added to a topic that is important to you.
Monograph

This section of our blog is dedicated to providing information and education for zoo and wildlife handlers on health conditions, treatments, and compounds for non-domestic and exotic animals, including topics about antibiotics, reversals, immobilization & sedation and steroids. Be sure to sign up to be notified when new posts are added to a topic that is important to you.
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Monograph Therapeutic Class Diuretic (Carbonic Anhydrase Inhibitor)
Monograph Therapeutic Class Systemic Hormonal Diagnostic Agent (Steroid Hormone)
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NexGen Blog

The NexGen Blog is filled with informational resources to support those who own or care for equines, wildlife, companion animals and zoo animals.
Most Recent Posts
While many lifelong dog owners have never experienced their beloved canines suffering from gastric ulcers (stomach or intestinal ulcers), this malady is quite common among dogs. Also called gastroduodenal ulcer disease, this syndrome applies to ulcer …
Read MoreThe peril of intestinal parasites is a serious concern for dog owners. Parasites and worms can cause a variety of ailments which range from minor gastrointestinal upset, all the way up to life-threatening medical crises. Pets that have access to the …
Read MoreHearing an otherwise normal and healthy dog begin to wheeze, sneeze or cough persistently for the first time can be puzzling, alarming, or a combination of both—particularly if one has never heard these sounds before. Normal, transitory reactions to …
Read MoreWhile we may not like to think about it, nearly all dogs are infested with worms to one degree or another. Parasitic worms can affect a dog’s ability to absorb nutrients, damage the lining of its intestinal tract, and cause the dog to become very …
Read MoreThe word “anesthesia” comes from the Greek words meaning "lack of sensation."1 Anesthesia is achieved through the administration of drugs that depress nerve function. In general anesthesia, the patient is rendered completely unconscious for a proscri …
Read MoreBronchitis (also called tracheobronchitis) in dogs is a sudden or long term inflammation of the trachea and bronchial airways that can also extend into the lungs. It often occurs in dogs already affected by respiratory disease or a disorder of the lu …
Read MoreThe owners of companion animals have become significantly more knowledgeable and attentive regarding their pets’ health over the last few decades. In that time, a great deal has been learned—and shared by the veterinary medical community—as regard …
Read MoreThere may be situations that arise where your dog may require general anesthesia or sedation for routine medical services or surgical procedures. In some cases, certain medical diagnostic procedures may also require anesthesia or sedation. Anesthesia …
Read MoreEstradiol is a medication and naturally-occurring steroid hormone. It is an estrogen and is used mainly in hormone therapy. Estradiol Cypionate (ECP) is a pro-drug ester of Estradiol, a naturally occurring hormone that circulates endogenously within …
Read MoreEquine protozoal myeloencephalitis (EPM) is the most prevalent cause of neurologic disease of horses in the Americas (North, Central and South America). It is an extremely serious disease that can be difficult to diagnose due to the fact that its pre …
Read MoreEarly and accurate diagnosis of pregnancy in the mare is critical in determining her reproductive viability during the breeding season. Once a mare has been determined to be pregnant, her embryonic growth and fetal development may be accurately monit …
Read MoreShivers is a neuromuscular syndrome in horses that has been recognized for centuries.1 At certain times, this condition has been called “Shivers” or “Shivering,” but both refer to the same syndrome. Interestingly, the literature states that throughou …
Read MorePeople who love horses tend to really love horses, and that goes triple for the horse owner who has decided to move forward with breeding their mare. Whether it’s an individual horse owner with a prized mare or a breeding operation of pretty much any …
Read MoreThe gestation period of the mare is less well-defined as compared to many other mammals. In other words, the window for parturition in the mare is much broader than that of other mammals. Mares are seasonally polyestrus, which means that their breedi …
Read MoreIn relation to horses, and performance horses in particular, the word “fatigue” is typically used to denote a horse’s inability to continue to perform at the desired level. This may manifest as slowing down, not being able to jump as high as is opti …
Read MoreMonographsAcepromazineAcetazolamideAdrenocorticotropic Hormone (ACTH)AltrenogestAmikacin SulfateAminophyllineAtipamezole HCLAzithromycinBetamethasoneBuserelin AcetateButorphanol TartrateCalcium LevulinateChondroitin SulfateChloramphenicolChlorpheni …
Read MoreChemical sedation and anesthesia are integral parts of veterinary medicine in the zoo setting. Even the most basic clinical examinations require sedation or anesthesia, since most patients in the zoo are either too nervous, too fast or too dangerous …
Read MoreAs discussed several times in this space, mares seasonally polyestrus, which means that their estrous cycles depend on the season. A mare will undergo regular estrus cycles during late Spring, Summer and early Fall, and none during Winter. It is larg …
Read MoreMany mares posses the bona fides that warrant breeding, such as good temperament, conformation, bloodlines and talent, but age is also a very important consideration. Despite the fact that it isn’t at all uncommon to find mares bred during their 20s, …
Read MoreTherapeutic Class:Synthetic GnRH (Systemic Drug)General Notes: A synthetic nonapeptide analog of gonadotropin-releasing hormone (GnRH, luteinizing hormone-releasing hormone [LHRH], gonadorelin).Palliative treatment of advanced prostate cancer in hum …
Read MoreTherapeutic Class: Mucopolysaccharide (Systemic Drug) General Notes:Parenteral, high viscosity mucopolysaccharide used for synovitis. Contraindications: None on label. Adverse effects: Local reactions possible. Different products have different d …
Read MoreHorse owners and managers commonly report muscular fatigue of horses. Muscular fatigue can be caused by numerous disorders of several body systems, or it can be a function of (or a normal consequence of) prolonged exercise. The decreased ability of …
Read MoreThe management of large hoofstock in the wild or on preserves often necessitates live capture of specific individuals, and chemical immobilization is generally the most effective method for capturing these animals. Selective capture of deer and other …
Read MoreTherapeutic Class:Antifungal Agent (Systemic Drug)General Notes:Parenteral-aminoglycoside antibiotic that is active against a variety of bacteria, predominantly gram-negative aerobic bacilli, but also many staphylococci.Because of potential adverse e …
Read MoreHow long is a horse pregnant? Well, the short answer is 10 to 12 months, or from approximately 326 days to 354 days (although there have been cases where gestation for a mare has gone as long as 365 to 370 days). Most mares only carry one foal per pr …
Read MoreTherapeutic Class: Non-Steroidal Anti-Inflammatory Agent (NSAID, Systemic Drug) General Notes: NSAID FDA-approved for topical use in horses for local control of joint pain & inflammation. Rare cases of esophagitis have been reported in pati …
Read MoreTherapeutic Class: Alpha Agonist (Systemic Drug) General Notes: Direct vasodilator A derivative of guanabenz. The Molecular Weight of guanabenz is 231.08. Primarily indicated in conditions like hypertension. Used in racing and other performance …
Read MoreTherapeutic Class: Injectable Hematinic (Systemic Drug) General Notes: Injectable hematinic. Used with epoetin (EPO) in small animals. Contraindications: Do not give IV or SC. Known hypersensitivity to iron sucrose or iron dextran; presence …
Read MoreTherapeutic Class: Nonsteroidal Anti-Inflammatory Agent (Systemic Drug) General Notes: Nonsteroidal anti-inflammatory agent used in horses, cats (short-term), and dogs. Cautions: GI ulceration or bleeding, hypoproteinemia, breeding animals (esp …
Read MoreTherapeutic Class: Antifungal Agent (Systemic Drug) General Notes: Fungistatic antibiotic used primarily for ringworm and other dermatophytic infections; no effect on other fungi. Azole antifungal agents and terbinafine have largely supplanted …
Read MoreTherapeutic Class: Antiparasitic (Systemic Drug) General Notes: Used in dogs and cats to prevent heartworm disease by eliminating tissue stages of heartworm larvae and in cats to remove and control hookworms Used in cattle, horses, and sheep as …
Read MoreTherapeutic Class:Dissociative General Anesthetic, NMDA-Receptor Antagonist (Systemic Drug)General Notes:Dissociative general anesthetic that also inhibits N-methyl-D-aspartate (NMDA) receptors and may be adjunctively useful for controlling painContr …
Read MoreWhile most animals ultimately do well with general anesthesia in the hands of a dedicated veterinarian, the fact is that general anesthesia does pose inherent risks, and this is the case in both animal and human medicine. Exotic animals in the wild, …
Read MoreTherapeutic Class: Parenteral Muscle Relaxant (Systemic Drug) General Notes: Muscle relaxant (parenteral) adjunctive for anesthesia. Contraindications: None noted except concurrent use with physostigmine. Must be used with caution in induction …
Read MoreTherapeutic Class:Antifungal, Azole (Systemic Drug)General Notes:Original imidazole oral antifungal historically used for systemic mycoses, but newer agents are generally preferred.Contraindications: Known hypersensitivity; some believe ketoconazole …
Read MoreThe capture, restraint and handling of free-roaming wild mammals involves potential dangers to both the animals and humans involved. As a result, this area of veterinary medicine was largely neglected until the middle of the 20th Century, when wildli …
Read MoreEstradiol is a medication and naturally-occurring steroid hormone. It is an estrogen and is used mainly in hormone therapy. Estrogen therapy is currently being used widely by veterinarians treating intermittent upward patellar fixation (IUPF) in hors …
Read MoreClenbuterol HCl is a beta-2-adrenoceptor agonist; it is the only FDA-approved medication for horses with reversible bronchospasm and is often used to treat horses with inflammatory airway disease (IAD) and recurrent airway obstruction (RAO, commonly …
Read MoreClenbuterol hydrochloride is a β2-adrenergic agonist that is used in horses as a short-term bronchodilator. In the short-term, it is typically employed in the management of airway obstruction (eg, severe equine asthma [SEA], formerly known as recurre …
Read MoreXylazine hydrochloride, an α₂ class of adrenergic receptor, has long been used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals. In horses however, adverse effects included muscl …
Read MoreStanding sedation is a critical component in many key procedures done on-site and in the equine veterinary clinic. When choosing between the available sedation drugs, veterinarians must consider safety, cost effectiveness for the client and the pract …
Read MoreXylazine hydrochloride is used widely for the chemical restraint of exotic animals in biological research, surgical procedures and veterinary medicine. This non-narcotic drug can induce a sedative, analgesic and muscle relaxing effect by autonomic an …
Read MoreAtipamezole hydrochloride is a synthetic α2-adrenergic antagonist. Its chemical name is 4-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole hydrochloride.1 It is indicated for the reversal of the sedative and analgesic effects of dexmedetomidine hydro …
Read MoreClenbuterol is a β2-adrenergic agonist that is used in horses as a short-term bronchodilator for the management of airway obstruction and for chronic breathing ailments in horses such as Chronic Obstructive Pulmonary Disease (COPD, also known as "hea …
Read MoreLong ago, veterinarians discovered that there are many surgical and other medical procedures which can be carried out in standing horses if the appropriate combinations of physical and chemical restraint are employed. The ability to perform procedure …
Read MoreStrictly speaking, exotic animal medicine encompasses all zoo animals, wildlife, and nondomestic pets,1 and the modalities of treatment for zoo animals and wildlife are nearly identical. This of course includes physical as well as chemical immobiliza …
Read MoreEstradiol Cypionate is a pro-drug ester of Estradiol, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. A …
Read MoreEstradiol is a medication and naturally-occurring steroid hormone. It is an estrogen and is used mainly in hormone therapy. Estradiol cypionate (ECP) is used to induce estrus in horses. It is also used by veterinarians to treat estrogen-responsive in …
Read MoreDiclazuril is a triazinone antiprotozoal that is effective for treating infections caused by Isospora spp., Toxoplasma gondii, and Eimeria spp. and has been used for treating coccidiosis.1 Initially, diclazuril was approved in Europe and in the U.S. …
Read MoreClenbuterol is a substituted phenylaminoethanol and a long-acting beta-2 adrenergic agonist with sympathomimetic activity. Pharmacologically, clenbuterol selectively binds to and activates beta-2 adrenergic receptors in bronchiolar smooth muscle, the …
Read MoreAtipamezole, a synthetic drug with an imidazole structure, is a highly selective α2-adrenergic antagonist.1,2 Typically used to counteract the sedative, hypnotic, analgesic, and other effects produced by α2-adrenergic agonists (such as dexmedetomidin …
Read MoreWhile there are inherent risks to deep sedation over general anesthesia in veterinary medicine,1 it is generally accepted that sedation carries less risks compared to general anesthesia in most cases. “While no clear statistics exist regarding the mo …
Read MoreVeterinarians are regularly called upon to anesthetize a wide variety of exotic animals. For the purposes of this discussion, exotic animals are those non-domesticated species that are encountered in the field, in a zoo setting or those which have fo …
Read MoreTherapeutic Class: Alpha-2 Adrenergic Agonist (Systemic Drug)General Notes: Alpha-2 sedative analgesic used primarily in horses. Contraindications: Heart block, severe coronary, cerebrovascular or respiratory disease, chronic kidney disease. C …
Read MoreTherapeutic Class: B Vitamin (Systemic Drug) General Notes: B Vitamin necessary for nucleoprotein synthesis & normal erythropoiesis. Injectable or oral dosage forms. Folic acid deficiency may be seen in animals (especially cats) with proximal o …
Read MoreTherapeutic Class: First-Generation Antihistamine (Systemic Drug)General Notes: Serotonin antagonist antihistamine used primarily as an appetite stimulant in cats; can be useful in management of serotonin-syndrome in small animals. Has also been …
Read MoreTherapeutic Class: Glucocorticoid (Systemic Drug)General Notes: Glucocorticoid used most commonly in veterinary medicine as an inhaled aerosol. Has shown efficacy in treating feline asthma, dogs with chronic cough, & in horses for recurrent airwa …
Read MoreTherapeutic Class:Selective Serotonin Reuptake Inhibitor (SSRI) (Systemic Drug) General Notes:A selective serotonin reuptake inhibitor (SSRI) antidepressant that is FDA-approved for use in dogs and used extra-label in cats for a variety of behavior d …
Read MoreGeneral anaesthetics and/or sedatives can take a number of hours to wear off and in some cases can cause patients to appear drowsy for more than a day. General anesthetic in healthy animals pose little risk, however, morbidity due to anesthesia does …
Read MoreThe use and study of wild animals frequently involves physical handling and in some instances the performance of surgical or other stressful procedures. With few exceptions, the requirements for domestic species are typically those of pain relief and …
Read MoreHistorically, the pharmacological immobilization of wild animals can be traced back to certain South American tribes who used curare-coated arrows to take down prey animals. Curare is an alkoloidal neurotoxin and muscle relaxant that competes with ac …
Read MoreThe broad term “anesthesia” typically covers simple immobilization and recovery via heavy sedation as well as general anesthesia, despite these two modalities being distinctly different. The latter involves central nervous system depression resulting …
Read MorePerforming general anesthesia in the field can be impractical as well as stressful for wildlife managers, veterinarians and their support staff; even under ideal conditions, it can cause morbidity and mortality in animals.1 Thus, immobilization proto …
Read MoreField wildlife anesthesia is often necessary for both invasive (e.g., surgical) and noninvasive (e.g., blood collection, collaring, metabolic) procedures. Anesthesia for noninvasive procedures is commonly utilized for the safety of the investigators …
Read MoreChemical immobilization consists of the use of chemical anesthetic and/or sedation agents to subdue, restrain or immobilize wildlife. The reasons for employing chemical immobilization in the field generally include research studies, conservation and …
Read MoreIn the mid-20th Century, the chemical immobilization of exotic animals became of increasing necessity, but at that time, there were no protocols nor procedures in widespread use in the field of wildlife management. In the late 1950s, the first comple …
Read MoreTherapeutic Class: Macrolide Antibiotic (Systemic Drug) General Notes: Macrolide antibiotic that may useful in the treatment of atypical mycobacterial infections or Helicobacter spp infections in dogs, cats, and ferrets and Rhodococcus …
Read MoreTherapeutic Class: Histamine2 Blocker (Systemic Drug)General Notes: Prototype histamine2-blocker primarily used to reduce GI acid production. Newer H2-blockers (eg, ranitidine, famotidine) and other antacid agents (eg, omeprazole) may be more e …
Read MoreTherapeutic Class: Reproductive Hormone (Systemic Drug)General Notes: Human glycoprotein hormone that mimics luteinizing hormone; used for a variety of theriogenology conditions in many species. Only for parenteral administration. Contraind …
Read MoreTherapeutic Class: Nutritional Supplement (Systemic Drug) General Notes: Dietary supplement (not an approved drug) that may be useful as an adjunctive treatment for osteoarthritis or other painful conditions in horses, cats, & dogs; FLUTD in c …
Read MoreTherapeutic Class:Skeletal Muscle Relaxant (Systemic Drug)General Notes: Direct-acting muscle relaxant.Primary indications: Horses: postanesthesia myositis/acute rhabdomyolysis; Dogs & Cats: functional urethral obstruction, potentially rhabdomyolysi …
Read MoreTherapeutic Class: Antiprotozoal/Coccidiostat (Systemic Drug)General Notes: Coccidiostat Not FDA approved for lactating dairy animals or laying chickens. Not effective against adult coccidia; no effect on clinical coccidiosis; results in treating …
Read MoreTherapeutic Class: Antihistamine (Systemic Drug)General Notes: An alkylamine antihistamine used primarily for its antihistamine and antipruritic effects; occasionally used for CNS depressant (sedative) effects. Contraindications: Hypersensiti …
Read MoreTherapeutic Class: Sedative/Antiemetic (Systemic Drug) General Notes: Prototype phenothiazine used primarily as an antiemetic; may be particularly useful in treating motion sickness in cats. Generally contraindicated in horses. Negligible …
Read MoreTherapeutic Class:Broad-Spectrum Antibacterial (Systemic Drug)General Notes:Broad-spectrum antibiotic with good penetration to most tissues, including the eye, CNS, and prostate.Banned in food animals. Should be avoided or used with extreme caution i …
Read MoreEquine Protozoal Myeloencephalitis (EPM) is a neurologic disease in horses caused by infection with the protozoan Sarcocystis neurona. The parasite infects horses when they ingest the S. neurona organism in contaminated feed or water. The definitive …
Read MoreEstradiol Cypionate is a pro-drug ester of Estradiol, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. A …
Read MoreSarcocystis neurona is a protozoan apicomplexan parasite that causes the neurological disease equine protozoal myeloencephalitis (EPM) in horses residing in the Americas.1 EPM is considered to be the most serious infectious neurologic disease of hors …
Read MoreTherapeutic Class: Hormonal Agent (Systemic Drug) General Notes: Synthetic GnRH analog indicated to induce ovulation in estrual mares. It is especially useful in artificial insemination and estrus synchronization programs. Deslorelin acetat …
Read MoreTherapeutic Class: Glucocorticoid (Systemic Drug) General Notes: Injectable, oral, and ophthalmic glucocorticoid A specific diagnosis is needed before glucocorticoids are administered, as they can mask disease. A course of treatment should b …
Read MoreTherapeutic Class: Hormonal Agent (Estrogen) (Systemic Drug) General Notes: Natural estrogen salt used primarily to induce estrus; has been used as an abortifacient (rarely recommended today). Contraindications: Pregnancy (as it is abortifa …
Read MoreTherapeutic Class: Antiparasitic Agent (Systemic Drug) General Notes: Anthelmintic useful for reduction and removal of nematode and protozoal parasites in a variety of species. Adverse effects may include hypersensitization reactions caused …
Read MoreTherapeutic Class: Macrolide Antibiotic, Prokinetic (Systemic Drug) General Notes: Macrolide antibiotic most commonly used (with rifampin) in foals; uncommonly used in dogs and cats. Prokinetic agent, at doses much lower than required for t …
Read MoreTherapeutic Class:Tetracycline Antibiotic (Systemic Drug)General Notes: Oral & parenteral tetracycline antibiotic.Bone & teeth abnormalities are much less likely than with other tetracyclines, but drug should be used with caution in pregnant & young …
Read MoreTherapeutic Class: Fluoroquinolone Antibiotic (Systemic Drug)General Notes: Veterinary oral and injectable fluoroquinolone antibiotic effective against a variety of pathogens; not effective against anaerobes. In dogs, oral bioavailability is be …
Read MoreVeterinarians first described the set of symptoms that would come to be known as equine protozoal myeloencephalitis (EPM) in 1968.1 In the 1970s, researchers determined that this this devastating neurologic illness was caused by a protozoan, although …
Read MoreDiclazuril is a triazinone antiprotozoal that is effective for treating equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona. It is also used in treating infections caused by Isospora spp., Toxoplasma gondii, and Eimeria spp,1 and a …
Read MoreEquine protozoal myeloencephalitis (EPM) continues to frustrate North American horse owners and veterinarians as one of the most common neurologic diseases in horses–and one of the most challenging to diagnose and treat.1 (EPM) is caused by the proto …
Read MoreEquine protozoal myeloencephalitis (EPM) is a disease of horses that affects the central nervous system. The primary causative agent for EPM is Sarcocystis neurona, a protozoan organism. The disease was described in the 1960s as segmental myelitis. B …
Read MoreIn wildlife medicine, it is often necessary to chemically restrain animals to perform even the most basic procedures. This is particularly true when working with large animals, particularly large carnivores. Therefore, it is important for veterinaria …
Read MoreThere are currently over 2,400 zoos in the United States, and all of them have animals that require routine veterinary care and, occasionally, more invasive medical procedures. The “first responders” and first line of defense in a zoo medical program …
Read MoreThere is little difference between indigenous or exotic animals in a zoo setting versus in the wild, save for the inherent stressors involved in being in captivity. Whether dealing with a fox or a tiger in a zoo setting, these animals will periodical …
Read MoreThe capture of free-ranging animals is an important foundation of wildlife research and preservation. Minimizing harm to wildlife, and especially mortality, is a vital ethical concern.Veterinarians and animal care specialists who are familiar with a …
Read MoreNatural resource management and research programs conducted in natural areas often require the administration of pharmaceuticals to wildlife. Pharmaceuticals commonly used in wildlife programs include anesthetic agents, sedatives, antibiotics, vacci …
Read MoreWhile inhalant anesthetics remain the “gold standard” for anesthesia in veterinary medicine, there are many circumstances in which the veterinarian will opt for sedation rather than general anesthesia, particularly when exotic species are consi …
Read MoreWildlife veterinarians are licensed animal health professionals who specialize in treating many different types of wildlife, including birds, amphibians, reptiles, and mammals. They may work either in a veterinary office setting or in the field, but …
Read MoreWildlife medicine treats, rehabilitates and conserves wild animal species.1 This differs from wildlife rehabilitation, in which the focus is on individual animals and where the goal is to care for each animal until it can be released back into the wi …
Read MoreDiclazurilTherapeutic Class:Antiprotozoal (Systemic Drug)General Notes: FDA-approved (in US) for equine protozoal myeloencephalitis (EPM) in horses & as a coccidiostat in broiler chickens.In small animals may be given with or without food. If animal …
Read MoreBased on the available literature, the most favorable age group for breeding horses is with mares between the ages of 4 and 12. Once the mare surpasses the age of 12—and particularly if it’s a maiden mare—the conventional wisdom dictates that issues …
Read MoreAcepromazine Therapeutic Class: Sedative General Notes: Required doses used may be lower than those listed on the approved label. Relatively long duration of action Negligible analgesic effects alone, but can potentiate effects o …
Read MoreAcetazolamide Therapeutic Class: Diuretic (Carbonic Anhydrase Inhibitor) General Notes: Used for metabolic alkalosis or glaucoma (open angle glaucoma) in small animals and hyperkalemic periodic paralysis (HYPP) in horses. Contraindic …
Read MoreAdrenocorticotropic Hormone (ACTH) Therapeutic Class: Systemic Hormonal Diagnostic Agent (steroid hormone) General Notes: Stimulates cortisol release; used primarily to test for hyper- or hypoadrenocorticism (ACTH-stimulation test); use as …
Read MoreAltrenogest Therapeutic Class: Progestin (Systemic Drug) General Notes: Progestational drug used in horses to suppress estrus or maintain pregnancy when progestin deficient; used in swine to synchronize estrus. Available commercially …
Read MoreAmikacin SulfateTherapeutic Class: Antibiotic (Systemic Drug) General Notes: Parenteral aminoglycoside antibiotic with good activity against a variety of bacteria, predominantly gram-negative aerobic bacilli and staphylococci. Adverse effe …
Read MoreAtipamezole HCLTherapeutic Class:Alpha-2 Adrenergic Antagonist (Systemic Drug)General Notes:Alpha-2 adrenergic antagonist; reverses the effects of agonists such as dexmedetomidine, medetomidine, and xylazine.No safety data on use in pregnant or lact …
Read MoreAzithromycinTherapeutic Class: Macrolide Antibiotic (Systemic Drug) General Notes: Oral and parenteral macrolide antibiotics; potentially useful for treating a variety of bacterial infections in veterinary patients; not effective for treating …
Read MoreBetamethasoneTherapeutic Class:Glucocorticoid (Systemic Drug) General Notes:Injectable glucocorticoid. Long acting; 25 to 40 times more potent than hydrocortisone; no mineralocorticoid activity.Primary use is intra-articular administration in horse …
Read MoreBuserelin AcetateTherapeutic Class:Hormonal Agent (Systemic Drug) General Notes:Buserelin is a synthetic gonadotropin-releasing hormone (GnRH) analogue that is designed to alter hormone levels.Typically employed in order to induce ovulation in cycl …
Read MoreButorphanol TartrateTherapeutic Class:Opiate Partial Agonist (Systemic Drug) General Notes: Partial opiate agonist/antagonist used in a variety of species as an analgesic, premedication, antitussive, or antiemetic.Reasonably good analgesic for hors …
Read MoreCalcium LevulinateTherapeutic Class:Mineral Supplement (Systemic)General Notes:The most soluble form of calcium Highest elemental calcium in ionic form Non - irritant form of calcium Vitamin D3 (Cholecalciferol)Helps in mobilization & absorption of …
Read MoreAminophyllineTherapeutic Class:Bronchodilator (Systemic Drug)General Notes: Parenteral form of theophylline; bronchodilator drug with diuretic activity. Used short-term for bronchospasm and cardiogenic pulmonary edema. For oral use, see theophylli …
Read MoreResearchers and local authorities frequently call upon veterinarians and animal control agents to help capture wild animals unharmed, to relocate animals unharmed in the course of their work, and to safely release animals from traps. It is theref …
Read MoreMany horse owners have come to their equine veterinarian or favored expert with the same question: They have a wonderful mare that they're thinking about breeding, but they're afraid she might be too old. Perhaps she's always been healthy, but they d …
Read MoreMany horse owners have entertained the notion of breeding their own prized mare. The idea of producing a foal with traits similar to its mother (or superior to its mother) can be very attractive. It is advisable that the novice horse breeder is a …
Read MoreGiven the wear and tear so many horses undergo as a result of their lifestyles (and, to be fair, ours), the field of veterinary medicine is continually searching for novel medications and new methods for pain relief in horses. "Managing pain in h …
Read MoreOn horse farms, the breeding shed is perhaps the most important place for accurate recordkeeping.1 Understanding as much as possible regarding the mare's breeding cycle can give horse owners and breeders an edge with regard to achieving their b …
Read MoreMuscle strains resulting in soreness can occur in a muscle or any group of muscles in the horse. Apart from serious injury, arthritis or other degenerative joint diseases (DJDs) however, back soreness is one of the most prevalent chronic issues i …
Read MoreWhether it's the manager of a breeding operation with numerous horses and a schedule to keep, or someone with a beloved mare they'd like to see pass on their genes for the next generation of equestrians in the family, the question of when a mare …
Read MoreUnlike most of the domesticated animals with which humans interact (dogs, cats, birds and the like), horses are often called upon to perform very hard work. Due to the nature of the activities in which horses engage, and in which many people enjo …
Read MoreWhat horse owners and breeding managers would give for a resource or utility that would allow them to precisely predict the day a mare will ovulate! While there are numerous online resources and charts that can reliably predict parturition based …
Read MoreGastric ulcers are common in horses and can affect any horse at any age. In fact, the prevalence of gastric ulcers in horses has been estimated at between 50% to 90%, depending on the populations surveyed and type of activity in which the horse i …
Read MoreDespite their relatively long gestation period of 335 to 360 days, horses have the potential for fairly high reproductive performance.1 Understanding as much as possible regarding the mare's breeding cycle can give horse owners and breeders an ed …
Read MoreMany procedures that are routinely accomplished in domestic animals with minimal restraint require anesthesia for the welfare and safety of both the zoo animal and veterinarian. Therefore, the chemical immobilization of wild and exotic animals in …
Read MoreA working knowledge of the mare’s reproductive anatomy and physiology is essential in a horse breeding program. Familiarity with the mare's estrous cycle and the timing of events therein is equally important. These provide the basis on which all …
Read MoreEven occasional equestrians—those who ride recreationally at the local stable or farm every now and then—can attest to the fact that running into a horse with a nervous disposition is extremely common. Sometimes, a horse's nervousness is apparent …
Read MoreDue to the demands placed upon horses that have to work for a living, there is a wealth of information available regarding how to manipulate the mare's cycle in order to keep her out of heat.Typical signs that a mare is in season include holding …
Read MoreThe direct administration of anti-inflammatory drugs into joints to provide relief from discomfort remains a common practice in many sectors of the equine industry. Unfortunately, many of these medications are corticosteroids, which have become c …
Read MoreMares have a gestation period of about 340 days. Because of this relatively long pregnancy, they must become pregnant again shortly after giving birth in order to produce a foal at about the same time each year if this is desired by the owner or …
Read MoreEquine protozoal myeloencephalitis (EPM) is a disease that affects the central nervous system of horses and which is caused by the protozoal organism. The name given to the protozoan organism shown to be the primary causative agent for EPM is Sarc …
Read MoreMares cycle when days are long and there is abundant daylight during most of the day, meaning that under normal circumstances, they cycle in the Spring, Summer and Fall. Mares do not cycle in Winter when daylight is short; this is known as anestr …
Read MoreEquine protozoal myeloencephalitis (EPM) is a disease of the horse that affects the central nervous system. Equine obviously refers to the horse, protozoal refers to the type of organism that causes the disease and myeloencephalitis refers to tha …
Read MoreHorse owners and breeders are continually on the lookout for ways to help improve their mares’ chances of becoming pregnant. One way that veterinarians are able to help is by administering prostaglandins.1 There are several forms of prostaglandin …
Read MoreSince wild animals are, well... wild, this dictates that any manipulation requiring handling will also necessitate chemical immobilization. Wildlife veterinarians are not only required to possess the normal complement of skills and qualifications …
Read MoreGenerally speaking, the best time for mating of a mare and stallion is determined by several factors. These include the length of daylight (season), the daily temperature, the mare's general health, diet, the amount of rainfall, the climate, and …
Read MoreHorse owners, managers and veterinarians are frequently faced with a need to to calm excitable horses or to provide relief from minor pain, or to facilitate minor or minimally-invasive procedures such as bronchoscopy, bronchoalveolar lavage, naso …
Read MoreMares are seasonally polyestrus; this means that they experience regular estrus cycles during late Spring, Summer and early Fall, with none occurring during the Winter. The typical mare cycles regularly between March and October, with each estrou …
Read MoreThere is a wide variety of pain relievers available for horses that can help alleviate pain and discomfort associated with injury or daily exercise, and enable easier, prompt treatment of the problem at hand.Methods of managing pain in horses ran …
Read MoreDuring the fetal development of the mare itself, a pool of primordial follicles forms as ovarian tissue, and each follicle consists of prophase I oocytes surrounded with a single layer of flattened granulosa cells.1 By the time the mare reaches s …
Read MoreThe nature of wild animals dictates that any manipulation that requires handling will necessitate chemical immobilization. Anaesthetizing wild animals is typically done to mark an animal, to apply a radio transmitter, administer individual …
Read MoreSince mares are seasonally polyestrus, they experience regular estrous cycles during late Spring, Summer and early Fall, and none during the Winter. These cycles are controlled by hormones, which respond to increases or decreases in daylight dura …
Read MoreAltrenogest is a progestational drug used in horses to suppress estrus or maintain pregnancy when progestin deficient. It is also used in pigs to synchronize estrus, and may be used in dogs for luteal deficiency or to prevent premature delivery …
Read MoreThe ovarian follicle is a fluid-filled sac surrounded by a group of cells that protect and nourish the ovum (egg). There are thousands of follicles in a mare’s ovaries, but usually only one begins to develop during each estrous cycle.1 By Day 16 …
Read MoreIn the case of a performance mare—one which races, for example—the reasons for preventing such a horse from coming into heat may be self-evident. The sort of behaviors often exhibited by mares in estrus—stamping, vocalizing, nipping, tail-swis …
Read More"Even the quietest of mares can turn into a proverbial fire-breathing dragon during her estrous cycle, which can make riding, training, competing, or handling these horses a challenge for any equestrian."1 Fortunately, over the years, veterinaria …
Read MoreThe fact that the horse is seasonally polyestrous makes this species a reproductive challenge for horsemen and equine practitioners. Mares will show several estrous cycles during the breeding season, assuming pregnancy does not terminate estrus. …
Read MoreA significant segment of the equine industry is involved with the breeding and of mares and the management of their breeding cycle. Given the sheer numbers of animals involved, this means that the economic considerations make it absolutely necess …
Read MoreThe estrous cycle (or oestrus cycle) is the group of physiological changes that occur in sexually mature female mammals which are brought on by reproductive hormones. The changes facilitate fertility and reproduction.Horses (mares) are seasonally …
Read MoreMares are seasonally polyestrus, meaning that they experience regular estrus cycles during late Spring, Summer and early Fall, and none during the Winter. These cycles are controlled by hormones, which respond to increases or decreases in dayligh …
Read MoreGonadotrophin-releasing hormone (GnRH) is a hormone produced by the hypothalamus in response to an increase in day length. As the hours of daily sunlight (or photoperiod) increase, melatonin levels subside, allowing GnRH to be produced. Productio …
Read MoreAltrenogest is a progestin of the 19-nortestosterone group commonly used to suppress or synchronize estrus in horses. It is used extensively in the reproductive management of mares to control the reproductive cycle, help maintain pregnancy, and h …
Read MoreMares are seasonally polyestrus, which means that they experience regular estrus cycles during late Spring, Summer and early Fall, and none during the Winter. These cycles are controlled by hormones, which respond to increases or decreases in day …
Read MoreMares are seasonally polyestrus, meaning that they experience regular estrus cycles during late Spring, Summer and early Fall, and none during the Winter. These cycles are controlled by hormones, which respond to increases or decreases in dayligh …
Read MoreThe administration of hormones to mares during breeding management is an essential tool for equine practitioners. Proper and timely administration of specific hormones to broodmares may be targeted to prevent reproductive disorders, to serve as a …
Read MoreDeslorelin acetate is a potent synthetic gonadotropin-releasing hormone (GnRH) analogue.1 According to the literature, the advantage to using deslorelin over hCG to induce ovulation is that it possesses a smaller molecular weight than hCG, making …
Read MoreBuserelin is a synthetic luteinizing hormone–releasing hormone (LHRH) analog. Like naturally occurring LHRH that is produced by the hypothalamus, initial or intermittent administration of buserelin stimulates release of luteinizing hormone (LH) a …
Read MoreIn general, the estrous cycle (or oestrus cycle) is the group of physiological changes that occur in sexually mature female mammals which are brought on by reproductive hormones. The changes facilitate fertility and reproduction.Horses (mares) ar …
Read MoreShe stamps and squeals when other horses pass her stall. She forgets her manners, swishing her tail and trying to nip when you groom and tack her up. And when you ride, she's a total airhead, ignoring your aids, whinnying, jigging and dancing, …
Read MoreVeterinary medicine is the branch of medicine that is concerned with health of animals; i.e., the maintenance of health and prevention, diagnosis and treatment of disease and injury in animals. This includes domesticated and wild animal specie …
Read MoreObviously, all animals have the potential for carrying diseases. Nearly all of us remember the warning we heard as children when we approached an unfamiliar animal or a small furry creature in the wild: "Don't touch that; you don't know where it' …
Read MoreAre there currently important unmet needs that exist in veterinary medicine, and if so, what are they and how might they be met?In developed nations, unmet needs in the realm of human medicine regularly make press reports, as economies rise or fa …
Read MoreThe subject of veterinary science is concerned with the treatment of a range of different animals; these include domestic pets, exotic pets, companion animals, performance animals, farmyard animals, zoo animals and wildlife. It encompasses an arra …
Read MoreAccording to the American Pet Products Association (APPA), revenue in the U.S. pet industry is expected to be $75.38 billion in 2019, with an estimated $18.1 billion of that figure slated for veterinary care.1 That is a decidedly impressive figur …
Read MoreVeterinarians are licensed professionals who are trained to diagnose and treat diseases and injuries in animals, as well as being educated in the prevention of disease and the maintenance of animal health. Most people are familiar with the role …
Read MoreHow is math used in veterinary medicine..?Typically, a veterinary degree require approximately six years of study at the university level, including a minimum of two years of pre-veterinary education and four years in a veterinary medicine progra …
Read MoreLeptospirosis is a bacterial infection caused by the spirochete Leptospira interrogans. The inoculation process involves bacteria penetrating the skin and spreading through the body by way of the bloodstream. Spirochetes are spiral or corkscrew-sh …
Read MoreIn brief, the field of zoology involves the study of animals at all levels, from their evolutionary origins, molecular and cell biology to their physiology, behavior and ecology. Veterinary science refers to the branch of medicine that deals with …
Read MoreThe most common cause of Acute Encephalitis Syndrome (AES) in horses is thought to be viral infection, although it is believed that it can also be brought on by bacterial, protozoan or fungal causes. Some researchers have designated AES as a grou …
Read MoreVeterinarians are the doctors of the animal world. They use their skills to evaluate patients, make diagnoses, and treat a wide range of conditions.1 For most people, the role of a veterinarian consists of maintaining their pet's (or pets') health …
Read MoreChlorpromazine is a phenothiazine tranquilizer. 1 While Chlorpromazine is often used by veterinarians as a centrally-acting antiemetic to prevent nausea and vomiting in dogs and cats, it has been widely used as a calming agent in performan …
Read MoreIn May 1998, the U.S. Food and Drug Administration (FDA) approved the use of a branded version of clenbuterol for the management of horses affected with airway obstruction, such as occurs in chronic obstructive pulmonary disease (COPD). In other …
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