As a result of individual temperament or being forced to engage in activities in which they wouldn’t normally engage in the wild (e.g., carrying a rider, walking into dark stables, traveling in a trailer, riding along busy roads) some horses develop excitability. In extreme cases, a horse may be so nervous or excitable that nearly every situation is a challenge.

Pain can be associated with poor behavior in excitable or difficult horses; thus, it is advisable to have a veterinarian assess any horse before making any changes or considering medications to address the issue. In some cases, excitability can be modified through training or diet.

Reserpine for Excitability in the Horse

Adverse effects of reserpine in horses are associated with decreased sympathetic tone and adrenergic inhibition. Common adverse effects reported in horses include diarrhea with or without signs of abdominal pain or colic (eg, pawing, getting up and down, pacing, restlessness, rolling, kicking or biting at side, stretching out/straining, shifting weight), muscle tremors/fasciculations, bradycardia, and hypotension.³

Where to buy Reserpine

Reserpine is available in the U.S. through pharmaceutical manufacturers and through veterinary custom compounding companies. 

This product carries numerous potential drug interactions. Please consult your veterinarian prior to beginning any treatment regimen.

FOR RX ONLY: A valid prescription from a licensed veterinarian is required for dispensing this medication.

¹equimed.com.

³Tobin T, et. al. Drugs and the performance horse. Springfield, IL: Charles C Thomas; 1981:245-260.